The progressive decline in the ability to maintain cellular homeostasis with age has been associated with dysfunctional organelles in a tissue-specific manner.
In our lab, we will study the link between organelles, longevity, and reproductive aging using the powerful model organism C. elegans . As organelles regulate central longevity pathways, understanding how their physiology changes with age will not only enhance our understanding of age-related processes but also reveal novel interventions with a yet unknown potential to improve age-related dysfunctions.